Baseline airway hyperresponsiveness and its reversible component: role of airway inflammation and airway calibre

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Baseline airway hyperresponsiveness and its reversible component: role of airway inflammation and airway calibre.

Airway hyperresponsiveness (AHR), in which airway inflammation has been reported to be a key factor, is an important component of asthma. However the precise role of inflammation in AHR is still unclear. In this report, airway inflammatory changes were assessed using hypertonic saline-induced sputum examination and exhaled nitric oxide analysis, and the relation between AHR to methacholine, air...

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Airway hyperresponsiveness (AHR) is a clinical feature of asthma and is often in proportion to the underlying severity of the disease. To understand AHR and the mechanisms that contribute to these processes, it is helpful to divide the airway components that affect this feature of asthma into "persistent" and "variable" categories. The persistent component of AHR represents structural changes i...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2000

ISSN: 0903-1936,1399-3003

DOI: 10.1034/j.1399-3003.2000.15b05.x